Abstract Topics

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Themes	Topics	Sub-Topics
β-Amyloid Diseases Alzheimer's Disease (AD), Prodromal AD, Cerebral Amyloid Angiopathy (CAA), Down Syndrome (DS) & Mild Cognitive Impairment (MCI) Tauopathies AD, Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), Pick's Disease & Chronic Traumatic Encephalopathy α-Synucleinopathies Parkinson's Disease (PD), PD Dementia, Dementia with Lewy Bodies (DLB), Multiple System Atrophy (MSA), Olivopontocerebellar Atrophy (OPCA) TDP-43- and C9orf72-Related Diseases Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Lobar Degeneration (FTLD), Frontotemporal Dementia (FTD), ALS-FTD Spectrum Diseases Vascular Dementia Multi-Infarct Dementia (MID), White Matter Disease & Stroke Prion Diseases Creutzfeldt-Jakob Disease (CJD), Fatal Familial Insomnia (FFI) & Gerstmann-Straussler-Scheinker Disease (GSSS) Huntington's Disease (HD) & Other Neurodegenerative Disorders Demyelinating Diseases Multiple Sclerosis (MS), Leucodystrophy Lysosomal and Storage Diseases Gaucher, Niemann Pick etc. Psychiatric and Epileptic Symptoms in Neurodegenerative Diseases Patient Care & Caregiver Support	Disease Mechanisms, Pathophysiology	Abeta, tau, α-synuclein aggregation, misfolding, phophorylation, acetylation, modifications LRKK2, parkin, PINK1, DJ-1 Cell to cell transmission, spreading of pathology, prion-like Inflammation, metabolism, insulin Synaptic plastcity & synapse pathology cellular signalling, kinases, phosphatases, calcium, metal ions Lysosomes, ubiquitin, proteasome, ER stress, chaperones Mitochondrial dysfunction, oxidative damage, lipids, lipoproteins, membrane trafficking Glial cells, neurogenesis, neural networks, plasticity Vasculature, microbleeds, hypertension, angiogenesis, blood-brain barrier Neural networks, plasticity Transcriptional & translational regulation, micro RNAs Autophagy, apoptosis, cell death Modeling of disease progression, aging
	Therapeutic Targets, Mechanisms for Treatment	Abeta, pGlu-Abeta, tau, phosphorylation, truncation, α-synuclein Immunotherapy Secretases, proteases, kinases, other enzymes, ApoE, lipoproteins Neurotransmitters, dopamine, receptor-based TREM2 modulators, CD 33 ligands, checkpoint inhibitors Cell transplantation, neurotrophic, synaptic plasticity, repair, regenerative medicine, adult neurogenesis, Deep brain stimulation Anti-inflammatory, anti-oxidants Gene and RNAi therapy Protein aggregation, misfolding, chaperones
	Drug Development, Clinical Trials	Immunotherapy, immunomodulators Amyloid clearance, clearance of pathologial tau, aggregation inhibitors Secretase inhibitors & modulators, kinase inhibitors, phosphatase modulators Neuroprotective & mitochondrial compounds Neurotransmitter-based modulators, receptor ligands Vitamins, antioxidants, neuroprotective compounds Cell-based therapies Deep brain stimulation, transcranial magnetic stimulation Medicinal chemistry approaches, drug Repurposing, personalized medicines, regulatory aspects Non-pharmacological interventions
	Imaging, Biomarkers, Diagnostics	Structural MRI, MR spectroscopy Functional MRI PET, amyloid, tau, glucose SPECT Multimodal imaging CSF, blood, body fluid biomarkers EEG, brain mapping, MEG Cognitive, psychometric & behavioral tests
	Genetics, Epidemiology	Whole genome sequencing Disease-causing mutations GWAS, genetic associations, susceptibility & protective genes Aging Environmental risk factors Metabolic and cardiovascular Infectious and inflammation Other
	Cell, Molecular & Systems Biology	APP, APLP, Abeta, tau, tau isoforms, α-synuclein, ApoE, LRKK2, parkin, PINK1, DJ-1 Secretases, kinases, phosphatases Posttranslational modifications Growth factors, synaptic plasticity GCPR, nicotinic, sigma-1 & other receptors Network biology, connectome, protein-protein interations Metabolomics, transcriptomics, lipidomics, proteomics Epigenetics, histone modification, DNA methylation
	Animal Models	Transgenic rodents Primates, naturally occuring models Non-mamalian models Optogenetics
	Dementia, Cognitive & Motor Dyfunctions	Caregiver support, mobile applications, social networks, support devices & monitoring Cognitive training Motor coordination & exercise Quality of life Functional foods Behavioral & psychiatric symptoms Fall prevention & patient protection